Allopurinol Sodium

CAS No. 17795-21-0

Allopurinol Sodium( —— )

Catalog No. M18135 CAS No. 17795-21-0

Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 27 Get Quote
10MG 35 Get Quote
25MG 80 Get Quote
50MG 115 Get Quote
100MG 174 Get Quote
200MG 257 Get Quote
500MG 696 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Allopurinol Sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
  • Description
    Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
  • In Vitro
    Allopurinol sodium (0, 10, 100, 1000 μg/ml; 17 h) decreases the expression of HIF-1α and HIF-2α protein in HFF and HUVEC cells.Allopurinol sodium (0, 10, 100, 1000 μg/ml; 24 h) reduces angiogenesis traits of HUVEC cells. Western Blot Analysis Cell Line:HFF, HUVEC cells Concentration:0, 10, 100, 1000 μg/ml Incubation Time:17 h Result:Reduced HIF-1α and HIF-2α protein expression in a dose dependent manner.
  • In Vivo
    Allopurinol sodium (39 mg/kg; p.o.; daily for 21 successive days) shows anti-depressant activity in mouse.Allopurinol sodium (10-400 mg/kg; i.p.) induces anti-nociception activity in mouse. Animal Model:20-30 g, male Swiss Albino mice Dosage:39 mg/kg Administration:P.o.; daily for 21 successive days Result:Reduced the immobility time in the FST with the immobility time of 129.8±10.5 s.Animal Model:30-40 g, male adult Swiss albino mice Dosage:10, 50, 100, 200, 400 mg/kg Administration:I.p.Result:Produced dose-dependent anti-nociception in the tail-flick, hot-plate.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    XO
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    17795-21-0
  • Formula Weight
    159.1
  • Molecular Formula
    C5H4N4NaO
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 50 mg/mL (314.27 mM)
  • SMILES
    [Na+].O=C1NC=NC2=C1C=NN2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mitsuboshi S, et al. J Pharm Health Care Sci. 2015 Oct 6;1:28.
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